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Study Background

What is Hypertension?

Resource Information

Patient Resources

National DNA repository

Recruitment Procedures
Acknowledgements

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Genome Screen Results

Investigators

Nursing and Scientific Teams


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SIBPAIR DEMOGRAPHICS

Table 1: Breakdown of 1708 family structures phenotyped for the MRC BRIGHT sibling pair study.

Family structure Number recruited
Affected sib pairs 1371
Affected sib trios 154
Affected sib quads 13
Affected sib quintets 1
Affected sibs with 1 parent 70
Affected sibs with 2 parents 16
Families with additional family members 83
Total phenotyped 1708

Table 2: Demographics of 1708 families phenotyped for the MRC BRIGHT sibling pair study

Phenotypic feature Demographics
Median Age at Diagnosis (interquartile range) 50 years (16)
Mean Age at Phenotyping (standard deviation) 63 years (10.6)
Mean Pre-diagnosis Systolic (standard deviation) 175 mm Hg (18)
Mean Pre-diagnosis Diastolic (standard deviation) 106 mm Hg (8)
Mean Systolic at Phenotyping (standard deviation) 156 mm Hg (21)
Mean Diastolic at Phenotyping mm Hg (standard deviation) 94 mm Hg (11)
Percentage with Systolic in top 5% for age 94%
Percentage with Diastolic in top 5% for age 84%
Percentage with ambulatory records 60%
Mean Body Mass Index (standard deviation) 27.7 kg/m2 (4)
Percentage above 30 Kg/M2 22% 22%
Median Waist/Hip ratio (interquartile range) 0.87 (0.14)
Median Alcohol intake females in units/week (interquartile range) 1 (5)
Median Alcohol intake males in units/week (interquartile range) 6 (14)

 

 



r.j.dobson@qmul.ac.uk