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Dr Martin Farrall (pubs from 1996)

Genome-wide association study identifies novel genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia
Am J Hum Genet. 2008 Jan 10; 82(1) pp. 139 - 149
Chris Wallace; Stephen J Newhouse; Peter Braund; Feng Zhang; Martin Tobin; Mario Falchi; Kourosh Ahmadi; Richard J Dobson; Ana Carolina B Marçano; Cother Hajat; Paul Burton; Panagiotis Deloukas; Morris Brown; John M Connell; Anna Dominiczak; G Mark Lathrop; John Webster; The Wellcome Trust Case Control Consortium; Martin Farrall; Tim Spector; Nilesh J Samani; Mark J Caulfield; Patricia B. Munroe

Genomewide association analysis of coronary artery disease.
N Engl J Med. 2007 Aug 2;357(5):443-53. Epub 2007 Jul 18.
Samani NJ, Erdmann J, Hall AS, Hengstenberg C, Mangino M, Mayer B, Dixon RJ, Meitinger T, Braund P, Wichmann HE, Barrett JH, König IR, Stevens SE, Szymczak S, Tregouet DA, Iles MM, Pahlke F, Pollard H, Lieb W, Cambien F, Fischer M, Ouwehand W, Blankenberg S, Balmforth AJ, Baessler A, Ball SG, Strom TM, Braenne I, Gieger C, Deloukas P, Tobin MD, Ziegler A, Thompson JR, Schunkert H, WTCCC

Genetic association analysis of inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) variants with essential hypertension.
J Med Genet. 2007 Jun 8; [Epub ahead of print]
Braga Marcano AC, Burke B, Gungadoo J, Wallace C, Kaisaki PJ, Woon PY, Farrall M, Clayton D, Brown M, Dominiczak A, Connell JM, Webster J, Lathrop M, Caulfield M, Samani N, Gauguier D, Munroe PB.

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
Nature. 2007 Jun 7;447(7145):661-78.
Wellcome Trust Case Control Consortium.

Chris Wallace, Ming-Zhan Xue, Stephen J. Newhouse, Ana Carolina B. Marçano, Abiodun K. Onipinla, Beverley Burke, Johannie Gungadoo, Richard J. Dobson, Morris Brown, John M. Connell, Anna Dominiczak, G. Mark Lathrop, John Webster, Martin Farrall, Charles Mein, Nilesh J. Samani, Mark J. Caulfield, David G. Clayton, and Patricia B. Munroe
Linkage Analysis Using Co-Phenotypes in the BRIGHT Study Reveals Novel Potential Susceptibility Loci for Hypertension.
Am J Hum Genet. 2006 Aug;79(2):323-31. Epub 2006 Jun 19.

Munroe PB, Wallace C, Xue MZ, B Marcano AC, Dobson RJ, Onipinla AK, Burke B, Gungadoo J, Newhouse SJ, Pembroke J, Brown M, Dominiczak AF, Samani NJ, Lathrop M, Connell J, Webster J, Clayton D, Farrall M, Mein CA, Caulfield M Increased Support for Linkage of a Novel Locus on Chromosome 5q13 for Essential Hypertension in the British Genetics of Hypertension Study.
Hypertension. 2006 Jun 5; [Epub ahead of print]

Bell JT, Wallace C, Dobson R, Wiltshire S, Mein C, Pembroke J, Brown M, Clayton D, Samani N, Dominiczak A, Webster J, Lathrop GM, Connell J, Munroe P, Caulfield M, Farrall M.
Two-dimensional genome-scan identifies novel epistatic loci for essential hypertension.
Hum Mol Genet. 2006 Apr 15;15(8):1365-74. Epub 2006 Mar 16

Sandosh Padmanabhan PhD, Chris Wallace Ph.D, Patricia B. Munroe Ph.D, Richard Dobson BSc, Morris Brown F.R.C.P, Nilesh Samani F.R.C.P, David Clayton B.A, Martin Farrall FRCPath, John Webster F.R.C.P, Mark Lathrop Ph.D, Mark Caulfield F.R.C.P, Anna F. Dominiczak F.R.C.P, John M. Connell F.R.C.P.
Chromosome 2p shows significant linkage to anti-hypertensive response in the British Genetics of Hypertension (BRIGHT) study.
Hypertension. 2006 Mar;47(3):603-8. Epub 2006 Jan 3.

S.J. Newhouse, C. Wallace, R. Dobson, C. Mein, J. Pembroke, M. Farrall, D. Clayton, M. Brown, N. Samani, A. Dominiczak, J.M. Connell, J. Webster, G.M. Lathrop, M. Caulfield, P. B. Munroe.
Haplotypes of the WNK1 gene associate with blood pressure variation in a severely hypertensive population from the British Genetics of Hypertension (BRIGHT) study.
Human Molecular Genetics. Jul 1;14(13):1805-14. Epub 2005 May 11.

Bouzekri N, Zhu X, Jiang Y, McKenzie CA, Luke A, Forrester T, Adeyemo A, Kan D, Farrall M, Anderson S, Cooper RS, Ward R. Angiotensin I-converting enzyme polymorphisms, ACE level and blood pressure among Nigerians, Jamaicans and African-Americans.
Eur J Hum Genet. 2004 Feb 18

Farrall M.
Quantitative genetic variation: a post-modern view.
Hum Mol Genet. 2004 Apr 1;13 Suppl 1:R1-7.

Farrall M.
Reports of the death of the epistasis model are greatly exaggerated.
Am J Hum Genet. 2003 Dec;73(6):1467-8; author reply 1471-3.

Caulfield M, Munroe P, Pembroke J, Samani N, Dominiczak A, Brown M, Benjamin N, Webster J, Ratcliffe P, O'Shea S, Papp J, Taylor E, Dobson R, Knight J, Newhouse S, Hooper J, Lee W, Brain N, Clayton D, Lathrop GM, Farrall M, Connell J; MRC British Genetics of Hypertension Study.
Genome-wide mapping of human loci for essential hypertension. Lancet. 2003 Jun 21;361(9375):2118-23.

Mayosi BM, Keavney B, Watkins H, Farrall M.
Measured haplotype analysis of the aldosterone synthase gene and heart size.
Eur J Hum Genet. 2003 May;11(5):395-401.

Mayosi BM, Keavney B, Kardos A, Davies CH, Ratcliffe PJ, Farrall M, Watkins H.
Electrocardiographic measures of left ventricular hypertrophy show greater heritability than echocardiographic left ventricular mass. Eur Heart J. 2002 Dec;23(24):1963-71.

Cox R, Bouzekri N, Martin S, Southam L, Hugill A, Golamaully M, Cooper R, Adeyemo A, Soubrier F, Ward R, Lathrop GM, Matsuda F, Farrall M.
Angiotensin-1-converting enzyme (ACE) plasma concentration is influenced by multiple ACE-linked quantitative trait nucleotides. Hum Mol Genet. 2002 Nov 1;11(23):2969-77.

Soubrier F, Martin S, Alonso A, Visvikis S, Tiret L, Matsuda F, Lathrop GM, Farrall M.
High-resolution genetic mapping of the ACE-linked QTL influencing circulating ACE activity.
Eur J Hum Genet. 2002 Sep;10(9):553-61.

Mead S, Mahal SP, Beck J, Campbell T, Farrall M, Fisher E, Collinge J.
Sporadic--but not variant--Creutzfeldt-Jakob disease is associated with polymorphisms upstream of PRNP exon 1.
Am J Hum Genet. 2001 Dec;69(6):1225-35. Epub 2001 Nov 05.

Lloyd SE, Onwuazor ON, Beck JA, Mallinson G, Farrall M, Targonski P, Collinge J, Fisher EM.
Identification of multiple quantitative trait loci linked to prion disease incubation period in mice.
Proc Natl Acad Sci U S A. 2001 May 22;98(11):6279-83.

Garner C, Tatu T, Reittie JE, Littlewood T, Darley J, Cervino S, Farrall M, Kelly P, Spector TD, Thein SL.
Genetic influences on F cells and other hematologic variables: a twin heritability study.
Blood. 2000 Jan 1;95(1):342-6.

Farrall M, Keavney B, McKenzie C, Delepine M, Matsuda F, Lathrop GM.
Fine-mapping of an ancestral recombination breakpoint in DCP1. Nat Genet. 1999 Nov;23(3):270-1.

Keavney B, McKenzie CA, Connell JM, Julier C, Ratcliffe PJ, Sobel E, Lathrop M, Farrall M.
Measured haplotype analysis of the angiotensin-I converting enzyme gene.
Hum Mol Genet. 1998 Oct;7(11):1745-51.

Munroe PB, Strautnieks SS, Farrall M, Daniel HI, Lawson M, DeFreitas P, Fogarty P, Gardiner RM, Caulfield M.
Absence of linkage of the epithelial sodium channel to hypertension in black Caribbeans.
Am J Hypertens. 1998 Aug;11(8 Pt 1):942-5.

Garner C, Mitchell J, Hatzis T, Reittie J, Farrall M, Thein SL. Haplotype mapping of a major quantitative-trait locus for fetal hemoglobin production, on chromosome 6q23.
Am J Hum Genet. 1998 Jun;62(6):1468-74.

Farrall M, Weeks DE.
Mutational mechanisms for generating microsatellite allele-frequency distributions: an analysis of 4,558 markers.
Am J Hum Genet. 1998 May;62(5):1260-2.

Rubio JP, Danek A, Stone C, Chalmers R, Wood N, Verellen C, Ferrer X, Malandrini A, Fabrizi GM, Manfredi M, Vance J, Pericak-Vance M, Brown R, Rudolf G, Picard F, Alonso E, Brin M, Nemeth AH, Farrall M, Monaco AP.
Chorea-acanthocytosis: genetic linkage to chromosome 9q21.
Am J Hum Genet. 1997 Oct;61(4):899-908.

Farrall M.
LOD wars: the affected-sib-pair paradigm strikes back!
Am J Hum Genet. 1997 Mar;60(3):735-8.

Bonyadi M, Rusholme SA, Cousins FM, Su HC, Biron CA, Farrall M, Akhurst RJ.
Mapping of a major genetic modifier of embryonic lethality in TGF beta 1 knockout mice.
Nat Genet. 1997 Feb;15(2):207-11.

Hughes DC, Allen J, Morley G, Sutherland K, Ahmed W, Prosser J, Lettice L, Allan G, Mattei MG, Farrall M, Hill RE.
Cloning and sequencing of the mouse Gli2 gene: localization to the Dominant hemimelia critical region.
Genomics. 1997 Jan 15;39(2):205-15.

Farrall M.
Affected sibpair linkage tests for multiple linked susceptibility genes.
Genet Epidemiol. 1997;14(2):103-15.

Farrall M.
Mapping genetic susceptibility to multiple sclerosis.
Lancet. 1996 Dec 21-28;348(9043):1674-5.

Caulfield M, Lavender P, Newell-Price J, Kamdar S, Farrall M, Clark AJ.
Angiotensinogen in human essential hypertension.
Hypertension. 1996 Dec;28(6):1123-5.

Todd JA, Farrall M.
Panning for gold: genome-wide scanning for linkage in type 1 diabetes.
Hum Mol Genet. 1996;5 Spec No:1443-8.



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