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Study Background

What is Hypertension?

Resource Information

Patient Resources

National DNA repository

Recruitment Procedures
Acknowledgements

Contact us

Genome Screen Results

Investigators

Nursing and Scientific Teams


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RESOURCE INFORMATION

The MRC BRIGHT study has recruited family-based and case control resources to provide a robust national repository for the evaluation of the genetic basis of hypertension.

The following table lists the major phenotypic and personal variables held for the genotyped family based resource. Variables are held relating to the following areas:

Ambulatory blood pressure (ABP)
Biochemistry
Electrocardiogram(ECG)
Personal and medical history
General Phenotypic measurements
Women only
Steroids records
Echocardiogram (Echo).

The genotyping results and associated data sit alongside this phenotypic data within the database. All phenotypic and genotypic data is available for download via this site to registered users.

SECTION VARIABLE
ABP ABP_on_Treatment
ABP Average_Daytime_Systolic
ABP Average_Daytime_Diastolic
ABP Mean_Daytime_BP
ABP Standard_Deviation_Daytime_BP
ABP Average_Nighttime_Systolic
ABP Average_Nighttime_Diastolic
ABP Mean_Nighttime_BP
ABP Standard_Deviation_Nighttime_BP
ABP Values_Above_Systolic_140
ABP Values_Above_Diastolic_90
ABP Oxford_Recorded_at_BRIGHT
ABP Oxford_Number_of_Anti_HT
Biochemistry Results LabNo
Biochemistry Results centre
Biochemistry Results Sodium
Biochemistry Results Potassium
Biochemistry Results Chloride
Biochemistry Results Urea
Biochemistry Results Cretinine
Biochemistry Results Calcium
Biochemistry Results Corrected_Calcium
Biochemistry Results asAlbumin
Biochemistry Results GGT
Biochemistry Results Glucose
Biochemistry Results Urate
Biochemistry Results Cholersterol
Biochemistry Results Tryglceride
Biochemistry Results HDL
Biochemistry Results UrinaryVolume
Biochemistry Results UrineTime
Biochemistry Results UrineSodium
Biochemistry Results UrineSodiumByVolume
Biochemistry Results UrinePotassium
Biochemistry Results UrinePotassiumByVolume
Biochemistry Results UrineCreatinine
Biochemistry Results UrineCreatinineByVolume
Biochemistry Results UrineAlbumin
Biochemistry Results AlbuminCreatinineRatio
Biochemistry Results CreatinineClearance
ECG ECG_ID
ECG RecDate
ECG REQBY
ECG System_Date
ECG Base_Flag
ECG Rate
ECG P_axis
ECG QRS_axis
ECG T_axis
ECG PR_interval
ECG QRS_duration
ECG QT_interval
ECG QTC_interval
ECG Minnesota_group1_L
ECG Serial_type1_1
ECG Minnesota_group1_P
ECG Serial_type1_2
ECG Minnesota_group1_A
ECG Serial_type1_3
ECG Minnesota_group2_1
ECG NoS1
ECG Minnesota_group2_2
ECG NoS2
ECG Minnesota_group3
ECG NoS3
ECG Minnesota_group4_L
ECG Serial_type1_4
ECG Minnesota_group4_P
ECG Serial_type1_5
ECG Minnesota_group4_A
ECG Serial_type1_6
ECG Minnesota_group5_L
ECG Serial_type1_7
ECG Minnesota_group5_P
ECG Serial_type1_8
ECG Minnesota_group5_A
ECG Serial_type1_9
ECG Minnesota_group6
ECG NoS4
ECG Minnesota_group7_1
ECG Serial_type1_10
ECG Minnesota_group7_2
ECG NoS5
ECG Minnesota_group8_1
ECG NoS6
ECG Minnesota_group8_2
ECG NoS7
ECG Minnesota_group8_3
ECG NoS8
ECG Minnesota_group8_4
ECG NoS9
ECG Minnesota_group9_L
ECG Serial_type1_11
ECG Minnesota_group9_P
ECG Serial_type1_12
ECG Minnesota_group9_A
ECG Serial_type1_13
ECG Minnesota_group9m_1
ECG NoS10
ECG Minnesota_group9m_2
ECG NoS11
ECG Serial_type2_1
ECG Serial_type2_2
ECG Serial_type2_3
ECG Serial_type2_4
ECG Serial_type2_5
ECG Serial_type2_6
ECG Serial_type2_7
ECG Serial_type_2_8
ECG Serial_type2_9
ECG Serial_type2_10
ECG Serial_type2_11
ECG Serial_type2_12
ECG Serial_type2_13
ECG Serial_type2_14
ECG Serial_type2_15
ECG Serial_type2_16
ECG Base_ECG_ID
Personal And Medical History Details Date_of_Birth
Personal And Medical History Details Place_of_Birth
Personal And Medical History Details Country_of_Birth
Personal And Medical History Details Other_Country
Personal And Medical History Details Postcode_Area
Personal And Medical History Details Postcode_at_Birth
Personal And Medical History Details Marital_Status
Personal And Medical History Details Educational_Level
Personal And Medical History Details Education_Years
Personal And Medical History Details School_Leaving
Personal And Medical History Details Qualifications
Personal And Medical History Details Employment
Personal And Medical History Details Occupation
Personal And Medical History Details Partners_Occuptation
Personal And Medical History Details In_Charge_of_Others
Personal And Medical History Details In_Charge_of_How_Many
Personal And Medical History Details Household
Personal And Medical History Details Previous_Renting
Personal And Medical History Details Any_Children
Personal And Medical History Details No_of_Children
Personal And Medical History Details Any_Adopted
Personal And Medical History Details Biological_Children
Personal And Medical History Details Affected_Biological_Children
Personal And Medical History Details Step_Parent
Personal And Medical History Details Which_Step_Parent
Personal And Medical History Details Adopted
Personal And Medical History Details Which_Child
Personal And Medical History Details No_of_Siblings
Personal And Medical History Details Sibling_Heart_Disease
Personal And Medical History Details Mother_Alive
Personal And Medical History Details Mother_Cause_of_Death
Personal And Medical History Details Mother_Age_of_Death
Personal And Medical History Details Father_Alive
Personal And Medical History Details Father_Cause_of_Death
Personal And Medical History Details Father_Age_of_Death
Personal And Medical History Details Any_Brothers
Personal And Medical History Details Is_Twin
Personal And Medical History Details Any_Half_Brothers
Personal And Medical History Details Any_Adopted_Brothers
Personal And Medical History Details No_of_Older_Brothers
Personal And Medical History Details No_of_Younger_Brothers
Personal And Medical History Details No_of_Living_Brothers
Personal And Medical History Details Brothers_Cause_of_Death
Personal And Medical History Details Brothers_Age_at_Death
Personal And Medical History Details Any_Brothers_Die_At_Birth
Personal And Medical History Details Any_Sisters
Personal And Medical History Details Any_Half_Sisters
Personal And Medical History Details Any_Adopted_Sisters
Personal And Medical History Details No_of_Older_Sisters
Personal And Medical History Details No_of_Younger_Sisters
Personal And Medical History Details No_of_Living_Sisters
Personal And Medical History Details Sisters_Cause_of_Death
Personal And Medical History Details Sisters_Age_at_Death
Personal And Medical History Details Any_Sisters_Die_At_Birth
Personal And Medical History Details FHx_of_Stroke
Personal And Medical History Details Which_Members_Had_Stroke
Personal And Medical History Details Age_Members_Had_Stroke
Personal And Medical History Details Mother_Stroke
Personal And Medical History Details Mother_Stroke_Age
Personal And Medical History Details Father_Stroke
Personal And Medical History Details Father_Stroke_Age
Personal And Medical History Details FHx_of_Angina
Personal And Medical History Details Which_Members_Had_Angina
Personal And Medical History Details Age_Members_Had_Angina
Personal And Medical History Details Mother_Angina
Personal And Medical History Details Mother_Angina_Age
Personal And Medical History Details Father_Angina
Personal And Medical History Details Father_Angina_Age
Personal And Medical History Details FHx_of_MI
Personal And Medical History Details Which_Members_Had_MI
Personal And Medical History Details Age_Members_Had_MI
Personal And Medical History Details Mother_MI
Personal And Medical History Details Mother_MI_Age
Personal And Medical History Details Father_MI
Personal And Medical History Details Father_MI_Age
Personal And Medical History Details Mother_HT_in_Pregnancy
Personal And Medical History Details Grandparents_Stroke
Personal And Medical History Details Grandparents_Angina
Personal And Medical History Details Grandparents_MI
Personal And Medical History Details Aunt_Uncle_Stroke
Personal And Medical History Details Aunt_Uncle_Angina
Personal And Medical History Details Aunt_Uncle_MI
Personal And Medical History Details Hx_of_HT
Personal And Medical History Details HT_Age_at_Diagnosis
Personal And Medical History Details HT_Age_at_Diagnosis_GP
Personal And Medical History Details Hx_of_Angina
Personal And Medical History Details Angina_Age_at_Diagnosis
Personal And Medical History Details Hx_of_Stroke
Personal And Medical History Details Stroke_Age_at_Diagnosis
Personal And Medical History Details Hx_of_Diabetes
Personal And Medical History Details Diabetes_Age_at_Diagnosis
Personal And Medical History Details Hx_of_MI
Personal And Medical History Details MI_Age_at_Diagnosis
Personal And Medical History Details Hx_of_High_Cholesterol
Personal And Medical History Details High_Cholesterol_Age_at_Diagnosis
Personal And Medical History Details Hx_of_Venous_Thromboembolism
Personal And Medical History Details Venous_Thromboembolism_Age_at_Diagnosis
Personal And Medical History Details Hx_of_Other_Conditions
Personal And Medical History Details Other_Conditions
Personal And Medical History Details Hx_of_CABG
Personal And Medical History Details Hx_of_Coronary_Angiograms
Personal And Medical History Details Hx_of_Coronary_Angioplasty
Personal And Medical History Details Taking_Anti_HT
Personal And Medical History Details Ever_on_Anti_HT
Personal And Medical History Details Months_Stopped_Anti_HT
Personal And Medical History Details Taking_Lipid_Lowering
Personal And Medical History Details Taking_Aspirin
Personal And Medical History Details Aspirin_for_Heart
Personal And Medical History Details Taking_Dietary_Supps
Personal And Medical History Details Special_Diet
Personal And Medical History Details Special_Diet_Reason
Personal And Medical History Details Vegetarian
Personal And Medical History Details Chest_Pain_Ever
Personal And Medical History Details Chest_Pain_when_Hurrying
Personal And Medical History Details Chest_Pain_when_Walking
Personal And Medical History Details Chest_Pain_Action_Taken
Personal And Medical History Details Chest_Pain_Medication
Personal And Medical History Details Chest_Pain_Relieved_When_Still
Personal And Medical History Details How_Long_To_Subside
Personal And Medical History Details Chest_Pain_Site
Personal And Medical History Details Chest_Pain_Top_Right
Personal And Medical History Details Chest_Pain_Top_Middle
Personal And Medical History Details Chest_Pain_Top_Left
Personal And Medical History Details Chest_Pain_Middle_Right
Personal And Medical History Details Chest_Pain_Centre
Personal And Medical History Details Chest_Pain_Middle_Left
Personal And Medical History Details Chest_Pain_Bottom_Right
Personal And Medical History Details Chest_Pain_Bottom_Middle
Personal And Medical History Details Chest_Pain_Bottom_Left
Personal And Medical History Details Told_Doctor_Chest_Pain
Personal And Medical History Details Chest_Pain_Doctor_Said
Personal And Medical History Details Severe_Chest_Pain
Personal And Medical History Details Told_Doctor_Severe_Chest_Pain
Personal And Medical History Details Severe_Chest_Pain_Doctor_Said
Personal And Medical History Details Breathless_Hurrying
Personal And Medical History Details Breathless_Walking
Personal And Medical History Details Stop_for_Breath_Walking
Personal And Medical History Details Breathlessness_Washing
Personal And Medical History Details Nocturnal_Breathlessness
Personal And Medical History Details Cigarettes_Now
Personal And Medical History Details Cigarette_Type
Personal And Medical History Details How_Many_Cigarettes
Personal And Medical History Details Cigarette_Tobacco
Personal And Medical History Details Cigarettes_Previously
Personal And Medical History Details How_Many_Cigarettes_Previously
Personal And Medical History Details Cigarette_Tobacco_Previously
Personal And Medical History Details Age_Stopped_Smoking
Personal And Medical History Details Age_Started_Smoking
Personal And Medical History Details Cigars
Personal And Medical History Details How_Many_Cigars_
Personal And Medical History Details Pipe
Personal And Medical History Details Pipe_Tobacco
Personal And Medical History Details Walk_To_Work
Personal And Medical History Details Minutes_Walk_To_Work
Personal And Medical History Details Walk_Otherwise
Personal And Medical History Details Minutes_Walk_Otherwise
Personal And Medical History Details Working_Activity_Level
Personal And Medical History Details Working_Significant_Exercise
Personal And Medical History Details Weekend_Activity_Level
Personal And Medical History Details Other_Activities
Personal And Medical History Details Activity_Type
Personal And Medical History Details How_Many_Years_Activity
Personal And Medical History Details Activity_Frequency_Winter
Personal And Medical History Details Activity_Frequency_Summer
Personal And Medical History Details Non_Working_Activity_Level
Personal And Medical History Details Non_Working_Significant_Exercise
Personal And Medical History Details Work_Days_Hours_of_Sleep
Personal And Medical History Details Non_Work_Days_Hours_of_Sleep
Personal And Medical History Details Alcohol_Intake
Personal And Medical History Details Changed_Drinking_Habits
Personal And Medical History Details Drinking_Habits_Previously
Personal And Medical History Details Reason_for_Changed_Drinking_Habits
Personal And Medical History Details Other_Reason_for_Changed_Drinking_Habits
Personal And Medical History Details Recent_Alcohol
Personal And Medical History Details Units_of_Spirits
Personal And Medical History Details Units_of_Wine
Personal And Medical History Details Units_of_Beer
Personal And Medical History Details Units_of_Low_Alcohol
Personal And Medical History Details Wine_Spirits_Session
Personal And Medical History Details Beer_Session
Personal And Medical History Details Maximum_Wine_Spirits_Session
Personal And Medical History Details Maximum_Beer_Session
Personal And Medical History Details Reason_for_Drinking
Phenotypic Data BP_Recording_Method
Phenotypic Data Single_Pulse
Phenotypic Data Single_Systolic
Phenotypic Data Single_Diastolic
Phenotypic Data First_Pre_Diagnosis_Pulse
Phenotypic Data First_Pre_Diagnosis_Systolic
Phenotypic Data First_Pre_Diagnosis_Diastolic
Phenotypic Data Second_Pre_Diagnosis_Pulse
Phenotypic Data Second_Pre_Diagnosis_Systolic
Phenotypic Data Second_Pre_Diagnosis_Diastolic
Phenotypic Data Third_Pre_Diagnosis_Pulse
Phenotypic Data Third_Pre_Diagnosis_Systolic
Phenotypic Data Third_Pre_Diagnosis_Diastolic
Phenotypic Data Mean_Pre_Diagnosis_Pulse
Phenotypic Data Mean_Pre_Diagnosis_Systolic
Phenotypic Data Mean_Pre_Diagnosis_Diastolic
Phenotypic Data BP_on_Treatment
Phenotypic Data Meets_Inclusion_Criteria
Phenotypic Data BP_Checked_Over_Weeks
Phenotypic Data Provide_Urinalysis
Phenotypic Data Urinalysis_Meets_Inclusion_Criteria
Phenotypic Data Which_Arm_BP
Phenotypic Data Left_Right_Handed
Phenotypic Data BP_Cuff
Phenotypic Data First_Pulse
Phenotypic Data First_Systolic
Phenotypic Data First_Diastolic
Phenotypic Data Second_Pulse
Phenotypic Data Second_Systolic
Phenotypic Data Second_Diastolic
Phenotypic Data Third_Pulse
Phenotypic Data Third_Systolic
Phenotypic Data Third_Diastolic
Phenotypic Data Mean_Pulse
Phenotypic Data Mean_Systolic
Phenotypic Data Mean_Diastolic
Phenotypic Data ECG_Recorded
Phenotypic Data First_Triceps
Phenotypic Data Second_Triceps
Phenotypic Data First_Biceps
Phenotypic Data Second_Biceps
Phenotypic Data First_Subscapular
Phenotypic Data Second_Subscapular
Phenotypic Data First_Suprailiac
Phenotypic Data Second_Suprailiac
Phenotypic Data Mean_Triceps
Phenotypic Data Mean_Biceps
Phenotypic Data Mean_Subscapular
Phenotypic Data Mean_Suprailiac
Phenotypic Data First_Height
Phenotypic Data Second_Height
Phenotypic Data First_Weight
Phenotypic Data Second_Weight
Phenotypic Data Mean_Height
Phenotypic Data Mean_Weight
Phenotypic Data BMI
Phenotypic Data Over_Clothes
Phenotypic Data First_Waist
Phenotypic Data Second_Waist
Phenotypic Data First_Hip
Phenotypic Data Second_Hip
Phenotypic Data Mean_Waist
Phenotypic Data Mean_Hip
Phenotypic Data Waist_Hip_Ratio
Phenotypic Data Willing_For_ABP
Phenotypic Data ABP_Obtained
Phenotypic Data ABP_20_Readings
Phenotypic Data Willing_For_24_Hour_Urine
Phenotypic Data Urine_24_Hour_Obtained
Phenotypic Data Urine_24_Hour_Volume
Phenotypic Data Venepuncture_Consent
Phenotypic Data Fasted_Sample
Phenotypic Data Fasted_Duration
Phenotypic Data Sample_1_Obtained
Phenotypic Data Sample_2_Obtained
Phenotypic Data Sample_3_Obtained
Phenotypic Data Sample_4_Obtained
Phenotypic Data Sample_5_Obtained
Phenotypic Data Sample_6_Obtained
Phenotypic Data Which_Arm_Venepuncture
Phenotypic Data Side_Effects_Venepuncture
Phenotypic Data What_Side_Effects_Venepuncture
Phenotypic Data Willing_For_Further_Venepuncture
Women Only Pregnant_Now
Women Only Ever_Pregnant
Women Only HT_Pregnancy
Women Only Which_HT_Pregnancy
Women Only Contraceptive_Method
Women Only HT_due_to_Contraception
Women Only Currently_Using_Contraceptive
Women Only How_Long_Stopped_Contraceptive
Women Only How_Long_Using_Contraceptive
Women Only Contraceptive_Brand
Women Only Menstruation
Women Only Age_Menstruation_Stopped
Women Only Womb_Operation
Women Only HRT_Ever
Women Only HRT_Now
Women Only Age_Began_HRT
Women Only Total_Years_on_HRT
Women Only Years_Stopped_HRT
Women Only HRT_Brand
Women Only HRT_Hormones
steroids centre
steroids THS
steroids THDOC
steroids Total_F
steroids THE
steroids THF
steroids aTHF
steroids Ratio
steroids Ratio_F_aF
steroids F
steroids E
steroids Ratio_F_E
steroids THB
steroids aTHB
steroids THA
steroids Ratio_B
steroids THALDO
steroids Andro
steroids Aetiochol
steroids DHA
steroids 5aOHAn
steroids 5aKetoAn
steroids 5aOHTest
steroids 5bOHAn
steroids 5bKetoAn
steroids aldosterone
steroids 18_OHB
steroids 18_OH_THA
steroids 18_OXO_F
steroids 18_OH_F
echo rhythm
echo m_mode
echo doppler
echo IVS
echo LVDd
echo PW
echo LVDs
echo FS
echo EF
echo E_vel
echo A_vel
echo Relax_time
echo deveraux
echo penn
echo BSA_mont
echo BSA_dubois_var

 

MRC Bright Study small image



r.j.dobson@qmul.ac.uk